Table.
Predictor | Discontinuation after cycle 1 |
Discontinuation after cycle 2 |
||
---|---|---|---|---|
AOR (95%CI)* | p-value** | AOR (95% CI)* | p-value** | |
Cycle failure point | ||||
No oocyte retrieval | 1.13 (0.77, 1.66) | 0.54 | 0.65 (0.40, 1.05) | 0.08 |
Failed fertilization | 1.09 (0.72, 1.67) | 0.68 | 1.29 (0.78, 2.13) | 0.33 |
Failed implantation | 1.00 (referent ) | 1.00 (referent ) | ||
Chemical pregnancy only | 1.51 (1.04, 2.17) | 0.03 | 1.09 (0.67, 1.76) | 0.74 |
Clinical pregnancy loss | 1.88 (1.22, 2.90) | <0.01 | 0.95 (0.52, 1.72) | 0.86 |
Woman’s age at cycle start | ||||
20–34 years | 1.00 (referent ) | 1.00 (referent ) | ||
35–39 years | 0.85 (0.65, 1.12) | 0.25 | 1.36 (0.98, 1.89) | 0.07 |
40–49 years | 1.12 (0.82, 1.52) | 0.49 | 1.46 (1.01, 2.11) | 0.05 |
Woman’s parity | ||||
No | 1.00 (referent ) | 1.00 (referent ) | ||
Yes | 1.58 (1.18, 2.10) | <0.01 | 1.66 (1.16, 2.37) | <0.01 |
Odds ratio (95% confidence interval) based on multivariate logistic regression including all variables shown, also controlling for study phase and study site. Cohort consisted of 2245 women commencing cycle 1.
Wald two-sided p-value.