TABLE 4.

Biochemical analysis of whole cell-free BAL, enumeration of RBC extravasation into the lung air space (BAL RBCs), and whole lung MPO activity from rats at 24 h after different pulmonary injuries: LC, CASP, or LC + CASP

Injury group	BAL total protein, µg/mL	BAL albumin, µg/mL	BAL total PL, µg/mL	BAL total protein to PL ratio,%	BAL RBCs	Whole lung MPO, units per lung
Uninjured	38 ± 2 (38)	4.9 ± 0.4 (5.1)	34.9 ± 1.9 (33.6)	110 ± 7 (117)	4.8 ± 1.7 × 10⁵ (3.9 × 10⁵)	0.15 ± 0.02 (0.14)
LC	726 ± 154 (612)^*	36.2 ± 6.5 (31.5)^*	54.0 ± 8.6 (49.0)	1,280 ± 120 (1300)^*	1.5 ± 0.4 × 10⁸ (1.2 × 10⁸)^*	1.16 ± 0.31 (0.92)^*
CASP	351 ± 90 (302)^*	32.6 ± 5.1 (28.6)^*	41.0 ± 6.3 (38.9)	906 ± 180 (911)^*	2.7 ± 0.7 × 10⁷ (2.7 × 10⁷)^*^†	1.99 ± 0.17 (1.91)^*
LC + CASP	814 ± 100 (797)^*^‡	52.8 ± 5.6 (51.4)^*^‡	45.0 ± 4.1 (48.3)	1,790 ± 120 (1,850)^*^†^‡	3.9 ± 1.1 × 10⁸ (2.5 × 10⁸)^*^‡	1.57 ± 0.32 (1.73)^*

Data are mean ± SEM (median), with n = 6 to 7 rats in each group. Significant differences from a specific group are indicated by

uninjured

^†

LC, or

^‡

CASP. Adjusting for multiple comparisons, differences were considered significant if P < 0.0042 to maintain a family-wise α error less than 0.05. PL indicates phospholipid.