TABLE 7.
Degree of statistical correlation between large surfactant aggregate protein and lyso-PC content and lung injury severity parameters
| Large aggregate total protein content | Large aggregate lyso-PC content | |||
|---|---|---|---|---|
| Lung injury parameters | r | P | r | P |
| BAL RBCs | 0.894 | <0.0001 | 0.847 | <0.0001 |
| BAL albumin | 0.859 | <0.0001 | 0.821 | <0.0001 |
| BAL total protein | 0.906 | <0.0001 | 0.894 | <0.0001 |
| BAL protein/phosphate | 0.918 | <0.0001 | 0.943 | <0.0001 |
| Lung MPO | 0.763 | <0.0001 | 0.865 | <0.0001 |
| BAL PMNs | 0.737 | <0.0001 | 0.837 | <0.0001 |
Pair-wise correlations and significance values were determined for the indicated parameters of large aggregate composition and lung injury severity based on pooled data for uninjured controls, LC at 24, 48, 72, and 96 h, and CASP and LC + CASP at 24 h (n = 40 – 43 for each correlation with large aggregate total protein content and n = 26 – 28 for each correlation with lyso-PC content).