. Author manuscript; available in PMC: 2010 Apr 1.

Published in final edited form as: Radiother Oncol. 2008 Nov 14;91(1):126–131. doi: 10.1016/j.radonc.2008.10.015

Table 1.

Effect of radiation on RIF-1 tumor volume over days in control and irradiated groups

	G	N	Time, hours
	G	N	0	24	48	72	96	120	144	192
Tumor volume, mm³	A	9	250±23	95±15	216±31	341±33	457±39	628±47	752±146	1290±245
	B	16	214±18	75±8	134.±14^A	185±22^A	277±39^A	400±40^A	494±44^A	785±245^A
	C	9	239±25	53±23	75±22^A	85±31^A	98±40^A	135±36^A	149±41^A	245±38^A
	D	24	220±26	75±7	91±11^A,^b	89±14^A ^a,^b	76±21^A ^a,^b	82±24^A ^a,^b	115±27^A,^a ^b	144±31^A,^a ^b,^E
	E	10	245±21	52±9	62±16^A	73±10^A	87±17^A	108±23^A	125±24^A	276±36^A

Abbreviations: G = groups. A, control group (sham-irradiated on day 0); B, single dose of 10 Gy radiation group (10 Gy on day 0); C, single dose of 20 Gy radiation group (20 Gy on day 0); D, 20 Gy oxygenated group (10Gy on day 0 and 10 Gy at 24 hr post first dose; E, 20 Gy hypoxic group (10Gy on day 0 and 10 Gy at 48 hr post first dose). N = numbers of animals. The values for time 0 are mean baseline absolute tumor volumes prior to the irradiation, while the values at other time points are relative mean changes in tumor volumes post irradiation. Differences between groups at the different time points were evaluated with unpaired t-test.

p < 0.05,

p < 0.01, compared with group A;

p < 0.01, compared with group B;

p < 0.05, compared with group E.