Table 1.
Transcripts whose expression was changed in the striatum of mice raised in EE in comparison to mice raised in SE
| Gene name (gene symbol) | Unigene | Diffrential expression (mean EE-mean ES) | z-ratio | p-values | Changes |
|---|---|---|---|---|---|
| Cell proliferation | |||||
| Cell cycle progression 2 protein (Cpr2) | Mm.196027 | 0.133 | 1.59 | 0.01 | + |
| Phosphoribosylglycinamide formyltransferase (Gart) | Mm.4505 | 0.151 | 1.81 | 0.04 | + |
| Prothymosin alpha (Ptma) | Mm.19187 | 0.142 | 1.70 | 0.01 | + |
| Nuclear autoantigenic sperm protein (Nasp) | Mm.7516 | 0.152 | 1.82 | 0.00 | + |
| Son cell proliferation protein (Son) | Mm.46401 | 0.141 | 1.69 | 0.02 | + |
| Cyclin in M2 (Cnnm2) | Mm.38506 | −0.258 | −3.09 | 0.03 | − |
| Cell differentiation | |||||
| Purkinje cell protein 2 (Pcp2) | Mm.41456 | 0.161 | 1.93 | 0.02 | + |
| Deltex 3 homolog (Dtx) | Mm.29197 | 0.129 | 1.54 | 0.02 | + |
| Embryonal stem cell specific gene 1 (Esg1) | Mm.139314 | 0.125 | 1.50 | 0.03 | + |
| Dickkopf 2 (Dkk2) | Mm.103593 | −0.550 | −6.59 | 0.03 | − |
| Signal transduction | |||||
| Eukaryotic translation initiation factor 1A (Eif1a) | Mm.143141 | 0.221 | 2.64 | 0.01 | + |
| Protein kinase C, lambda (Prkcl) | Mm.23823 | 0.212 | 2.53 | 0.01 | + |
| Mitogen-activated protein kinase kinase kinase 12 (Map3k12) | Mm.4358 | 0.182 | 2.18 | 0.00 | + |
| Leucine-rich and death domain containing (Lrdd) | Mm.158086 | 0.281 | 3.37 | 0.00 | + |
| Regulator of G-protein signaling 2 (Rgs2) | Mm.28262 | −0.130 | −1.56 | 0.02 | − |
| Transforming growth factor beta 1 induced transcript 4 (Tgfb1i4) | Mm.20927 | −0.132 | −1.58 | 0.00 | − |
| Polynucleotide kinase 3′- phosphatase (Pnkp) | Mm.29545 | −0.200 | −2.39 | 0.00 | − |
| Transcription/translation | |||||
| Immediate early response 2 (Ier2) | Mm.399 | 0.413 | 4.95 | 0.01 | + |
| Mitochondrial ribosomal protein L52 (Mrpl52) | Mm.30240 | 0.175 | 2.09 | 0.02 | + |
| Mitochondrial ribosomal protein S15 (Mprs15) | Mm.25143 | 0.198 | 2.37 | 0.00 | + |
| Proteasome 26S subunit, non-ATPase, 4 (Psmd4) | Mm.2261 | −0.223 | −2.67 | 0.02 | − |
| Activating transcription factor 3 (Atf3) | Mm.2706 | −0.156 | −1.86 | 0.05 | − |
| Structural proteins | |||||
| Synaptotagmin-like 4 (Sytl4) | Mm.38674 | 0.197 | 2.36 | 0.02 | + |
| Ubiquitously expressed transcript (Uxt) | Mm.34779 | 0.542 | 6.49 | 0.01 | + |
| Tissue inhibitor of metalloproteinase 4 (Timp4) | Mm.36851 | 0.154 | 1.84 | 0.01 | + |
| GPI-anchored membrane protein 1 (Gpiap1) | Mm.1098 | 0.133 | 1.59 | 0.03 | + |
| Vasodilator stimulated phosphoprotein (Vasp) | Mm.9684 | −0.139 | −1.66 | 0.02 | − |
| Actinin alpha 3 (Actn3) | Mm.5316 | −0.177 | −2.12 | 0.01 | − |
| Decorin (Dcn) | Mm.1987 | −0.152 | −1.82 | 0.04 | − |
| Actin, alpha 2, smooth muscle (Acta2) | Mm.16537 | −0.136 | −1.63 | 0.05 | − |
| Metabolism | |||||
| 6- pyruvoyl-tetrahydropterin synthase (Pts) | Mm.35856 | 0.196 | 2.34 | 0.03 | + |
| Glucosidase, alpha, acid (Gaa) | Mm.4793 | 0.127 | 1.52 | 0.05 | + |
| Similar to phosphoserine aminotransferase | Mm.29902 | 0.176 | 2.11 | 0.02 | + |
| Ring finger protein 14 (Rnf14) | Mm.22086 | 0.202 | 2.42 | 0.03 | + |
| Uridine-cytidine kinase 2 (Ck2-pending) | Mm.25309 | 0.195 | 2.33 | 0.01 | + |
| Mannosidase 1, beta (Man1b) | Mm.4389 | −0.570 | −6.82 | 0.01 | − |
| Others | |||||
| Requiem (Req) | Mm.2651 | 0.153 | 1.84 | 0.04 | + |
| MutS homolog 2 (Msh2) | Mm.4619 | 0.149 | 1.79 | 0.01 | + |
| T- cell immunoglobulin and mucin domain containing 2 (Timd2) | Mm.29550 | 0.159 | 1.90 | 0.02 | + |
| Tripartite motif protein 33 (trim33) | Mm.31048 | 0.365 | 4.37 | 0.05 | + |
| Centromere autoantigen A (Cenpa) | Mm.6579 | 0.206 | 2.47 | 0.04 | + |
| Ewing sarcoma homolog (Ewsh) | Mm.142822 | 0.169 | 2.02 | 0.04 | + |
| EH-domain containing 3 (Ehd3) | Mm.18526 | 0.147 | 1.76 | 0.04 | + |
| Pallidin (Pldn) | Mm.148195 | 0.129 | 1.55 | 0.04 | + |
| Dynamin 1-like (Dnm1l) | Mm.140013 | 0.168 | 2.01 | 0.01 | + |
| ATP-binding cassette, sub-family C, member 1b (Abcc1b) | Mm.196634 | 0.160 | 1.92 | 0.04 | + |
| Uncoupling protein 2, mitochondrial (ucp2) | Mm.144413 | −0.130 | −1.55 | 0.03 | − |
| Leucine zipper protein 1 (Luzp1) | Mm.92659 | −0.173 | −2.07 | 0.01 | − |