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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Mol Immunol. 2008 Jul 9;45(14):3731–3739. doi: 10.1016/j.molimm.2008.06.003

Fig. 2.

Fig. 2

B cells transfected with APE/Ref-1 AS and activated with anti-CD40 mAb proliferate faster than control cells. Mouse B cells were transfected with APE/Ref-1 AS or control (APE/Ref-1 ASREV) oligonucleotides, labeled with CFSE and stimulated with anti-CD40 mAb for 72 h. Cell divisions were determined using the Proliferation Wizard algorithm ModFit LT program (Version 2.0). (A) CFSE histograms of blasting B cells of one out three independent experiments; (B) the statistic analysis from data from three independent experiments expressed as percentages of cells in each generation and presented as means±S.D. *p < 0.05. Black and open histograms represent the percentage of APE/Ref-1 AS and control (APE/Ref-1 ASREV) cells in each generation, respectively; P indicates the parent generation. (C) The average of proliferation index from three independent experiments.