Table 4.
Age-adjusted hazard ratios (HR) and 95% confidence intervals (CI) of breast cancer tumor subtype associated with the degree of affected relatives1
| ER+/PR+ | ER+/PR- | ER-/PR- | ||||
|---|---|---|---|---|---|---|
| Relative with breast cancer | N | HR1 (95%CI) | N | HR1 (95%CI) | N | HR2 (95%CI) |
| No family history (Ref.) | 336 | 1.0 | 33 | 1.0 | 75 | 1.0 |
| 2nd degree history only | 124 | 1.11 (0.91-1.37) | 17 | 1.60 (0.89-2.87) | 27 | 1.02 (0.66-1.59) |
| Any 1st degree history | 181 | 1.49 (1.24-1.78) | 29 | 2.43 (1.47-4.01) | 36 | 1.36 (0.91-2.03) |
1
Estimated using Cox Proportional Hazards models among women in the Group Health Breast Cancer Screening Program between June 1, 2001 and December 31, 2005
2
Adjusted for age at baseline (quadratic)