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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Small. 2009 Feb;5(2):256–264. doi: 10.1002/smll.200800646

Figure 6.

Figure 6

Glioma cell invasion inhibition. (a) Functional inhibition of NPC, free CTX, and NP on MMP-2 in the presence of gelatin. Comparable inhibition by CTX and NPC indicates retention of catalytic activity of CTX bound to NPC. (b) Schematic of cell invasion assay. (c) Quantitative assessment matrigel cell invasion post-treatment. (d) Optical images of C6 cells (scale bar: 50 μm) and fluorescence images of EGFP-expressing C6 cells (scale bar: 20 μm) that have crossed through the pores of a matrigel invasion chamber, showing that NPC significantly limits cellular mobility compared to NP and CTX treatments.