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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Blood Cells Mol Dis. 2008 Apr 18;41(1):109–118. doi: 10.1016/j.bcmd.2008.01.008

Figure 1. SS mice have markedly abnormal blood smears.

Figure 1

Peripheral blood smears of EDTA-anticoagulated blood obtained by retrobulbar venous plexus puncture from WT, SS and β-thalassemia mice. Blood smears from SS animals show anisocytosis, poikilocytosis, sickled erythrocytes, target cells, erythrocyte fragments of varying sizes, Howell-Jolly bodies, and an increased percentage of polychromatophilic erythrocytes. In sharp contrast, smears from WT animals do not show any of these findings. Blood smears from β-thalassemia mice show anisocytosis, microcytosis, targets cells, erythrocyte fragments, and an increased percentage of polychromatophilic erythrocytes.