Table 1. Quantification of lamina neuron targeting phenotypes.
Percentage of mistargeted axons and branches and the total number of cells and animals examined are listed for each genotype and layer choice phenotype. For comparison, R7 and R8 are also included. Phenotypes are illustrated in Figure 2. DLar alleles used were Dlar2–127 and DlarC12. R8 targeting was scored in ey3.5FLP clones with Rh5-lacZ as a marker. A small percentage of both mutant and control R8s (numbers in parentheses) appeared to extend significantly deeper into the medulla (~M5) than the remaining R8s.
| Cell | Allele | Mistargeting [%] | Cells | Animals |
|---|---|---|---|---|
| L1 | CadN | 0 | 142 | 14 |
| CadNΔ14 | 29 | 332 | 16 | |
| CadNM19 | 22 | 189 | 10 | |
| Dlar | 0 | 155 | 9 | |
| L2 | CadN | 0 | 125 | 14 |
| CadNΔ14 | 0 | 121 | 16 | |
| CadNM19 | 0 | 62 | 10 | |
| Dlar | 0 | 90 | 9 | |
| L3 | CadN | 1 | 252 | 21 |
| CadNΔ14 | 81 | 375 | 31 | |
| CadNM19 | 25 | 338 | 26 | |
| Dlar | 0 | 76 | 16 | |
| L4 | CadN | 0 | 70 | 21 |
| CadNΔ14 | 81 | 129 | 15 | |
| CadNM19 | 65 | 268 | 17 | |
| Dlar | 0 | 105 | 14 | |
| L5 terminal | CadN | 0 | 25 | 4 |
| CadNΔ14 | 0 | 138 | 6 | |
| CadNM19 | 0 | 88 | 5 | |
| Dlar | 0 | 99 | 5 | |
| L5 branch | CadN | 0 | 25 | 4 |
| CadNΔ14 | 100 | 138 | 6 | |
| CadNM19 | 100 | 88 | 5 | |
| Dlar | 0 | 99 | 5 | |
| R7 | CadN | 0 | 87 | 4 |
| CadNΔ14 | 100 | 128 | 4 | |
| CadNM19 | 100 | 59 | 2 | |
| Dlar | 95 | 321 | 10 | |
| R8 | CadN | (3) | 187 | 2 |
| CadNΔ14 | (4) | 501 | 6 | |
| CadNM19 | (3) | 111 | 3 |