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The effect of GSNO on Cx46 and Cx46-CT43 hemichannels is reversed by DTT. Shown are representative whole cell recordings of Cx46 and Cx46-CT43 hemichannel currents after 40-min exposure to 1 mM GSNO in the absence of DTT (GSNO) or after 15-min exposure to 10 mM DTT (GSNO + DTT). See Fig. 2 for details.
