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. 2009 Mar 25;296(6):F1364–F1375. doi: 10.1152/ajprenal.90667.2008

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Fig. 2. — Rhcg immunolabel in Rhcg^fl/fl, Ksp-cadherin-Cre negative (Cre-negative) and Rhcg^fl/fl, Ksp-cadherin-Cre positive (Cre-positive) mice on a normal diet. A: Rhcg immunolabel in cortex of a kidney from an Rhcg^fl/fl, Ksp-Cre⁻ mouse. A normal distribution of Rhcg immunolabel in cortical collecting duct (CCD; arrows) and in connecting tubule (CNT) and distal convoluted tubule (DCT) segments (arrowheads) is present. B: Rhcg immunolabel in Rhcg^fl/fl, Ksp-Cre⁺ mouse kidney. No Rhcg immunolabel is evident in CCD (arrow). Rhcg immunoreactivity is present in CNT and DCT segments (arrowheads). C: Rhcg immunolabel in the outer medulla and demonstration of normal Rhcg expression in outer medullary collecting duct (OMCD) segments (arrows). D: outer medulla from Rhcg^fl/fl, Ksp-Cre⁺ kidney. No Rhcg immunolabel is detectable.