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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Heart Fail Clin. 2008 Apr;4(2):153–161. doi: 10.1016/j.hfc.2008.01.007

Figure 2.

Figure 2

Effects of statins on LV remodeling. Dahl salt sensitive rats (17 weeks) were treated with (A) low salt diet (B) high salt diet (C) high salt + cerivastatin. Panels D – F show the resultant cardiac fibrosis (arrow heads) at 17 weeks in (D) low salt diet (E) high salt diet and (F) high salt diet + cerivastatin treated rats (Modified with permission from Elsevier. Hasegawa H, Yamamoto R, Takano H, et al: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the development of cardiac hypertrophy and heart failure in rats. J Mol Cell Cardiol 35:953, 2003)