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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: J Neurochem. 2009 Jan 23;109(1):116–124. doi: 10.1111/j.1471-4159.2009.05921.x

Figure 1. Anticoagulant activity of human and mouse 3K3A-APC.

Figure 1

Modified APTT clotting assays were performed using human factor V deficient plasma containing 4% mouse plasma as a source of mouse factor V. Prolongation of clotting times were caused by human (—) or mouse (---) wild type wt-APC (circles) or 3K3A-APC mutants (triangles). APC concentrations indicate final amounts in the assay; h and m before APC denote human or murine APC, respectively.