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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Hypertension. 2008 Dec 29;53(2):158–165. doi: 10.1161/HYPERTENSIONAHA.108.121954

Figure 1.

Figure 1

MR blockade did not influence systolic blood pressure (SBP), but attenuated aortic tissue hypertrophy and RAAS activity in Ren2 rats. A, SBP was measured at the initial and final of experiment. B, Average aortic media thickness. C, Average gray scale intensities of immunostaining for MR. D, Representative immuostaining images for ANG II. E, Average gray scale intensities of immuostaining for ANG II. F, Representative immuostaining images for AT1R. G, Representative Western blot for AT1R (top, 50 kDa), bar graph showed the band densitometry analysis (bottom). The results are means ± SEM from 6-7 rats per group. ** P<0.01 vs. age-matched Sprague-Dawley controls (SD-C) (at the final); there was no significant difference of SBP between spironolacotne treated Ren2 (Ren2-Sp) and Ren2 controls (Ren2-C) (at the final). #P <0.05 vs. SD-C; *P<0.05 vs. Ren2-C. D and F, Magnification ×400, scale bar 50 μm.