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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Immunity. 2009 Mar 12;30(3):358–371. doi: 10.1016/j.immuni.2009.02.003

Figure 7. Foxo1 Control of IL-7R Expression and Homeostasis of OT-II T Cells.

Figure 7

(A) Expression of CD44 and CD62L in splenic OT-II T cells from WT and KO mice at 8 weeks old. These are representative results of three independent experiments.

(B) Expression of CD127 (IL-7R) in splenic OT-II T cells from WT and KO mice. These are representative results of three independent experiments. ISC stands for the iso-type control antibody.

(C) Number of splenic and lymph node (pLN) OT-II T cells from WT and KO mice aged between 8 and 12 weeks. The p values of cell number between the two groups of mice are shown.

(D) Percentage of splenic OT-II T cells from WT, KO, WT IL-7R transgenic (IL-7RTg), and KO IL-7RTg mice at 8 weeks old. These are representative results of three independent experiments.

(E) CD127 expression in splenic OT-II T cells from WT, KO, WT IL-7RTg, and KO IL-7RTg mice at 8 weeks old. ISC stands for the iso-type control antibody.

(F) Bcl-2 expression in splenic OT-II T cells from WT, KO, WT IL-7RTg, and KO IL-7RTg mice at 8 weeks old.