Table 2.
Correlation between new contrast enhancing lesions per scan over 6 months and relapse rate over 12 months
| Trial | n | Correlation (Spearman) |
p-value (Spearman) |
Correlation (Pearson) |
95% CI (Pearson) |
|---|---|---|---|---|---|
| Overall | 208 | 0.22 | 0.001 | 0.06 | −0.08, 0.19 |
| A | 1 | - | - | - | - |
| B | 4 | 0.32 | > 0.20 | 0.12 | −0.95, 0.97 |
| C | 3 | - | - | - | - |
| D | 11 | 0.03 | > 0.20 | 0.04 | −0.57, 0.63 |
| E | 33 | 0.23 | 0.20 | −0.04 | −0.38, 0.31 |
| F | 44 | 0.33 | 0.03 | 0.06 | −0.24, 0.35 |
| G | 27 | 0.04 | > 0.20 | −0.11 | −0.47, 0.28 |
| H | 13 | 0.11 | > 0.20 | −0.07 | −0.60, 0.50 |
| I | 18 | 0.04 | > 0.20 | 0.03 | −0.45, 0.49 |
| J | 26 | 0.28 | 0.17 | 0.07 | −0.33, 0.44 |
| K | 28 | 0.38 | 0.05 | 0.26 | −0.13, 0.58 |
| Combined* | 204 | 0.23 | 0.003 | 0.04 | −0.11, 0.18 |
*
Weighted mean correlation, trials A and C excluded (see text).