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. 1987 Aug;25(8):1490–1494. doi: 10.1128/jcm.25.8.1490-1494.1987

New infectious spirochete isolated from short-tailed shrews and white-footed mice.

J F Anderson, R C Johnson, L A Magnarelli, F W Hyde, T G Andreadis
PMCID: PMC269255  PMID: 3305565

Abstract

A spirochete with two periplasmic flagella was isolated from the blood or tissues of spleens and kidneys from short-tailed shrews (Blarina brevicauda) and white-footed mice (Peromyscus leucopus) in Connecticut and Minnesota. After inoculation, the shrew-mouse spirochete infected Swiss mice and Syrian hamsters. This spirochete is morphologically and serologically distinct from the species of Treponema, Borrelia, Leptospira, and Spirochaeta examined.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson J. F., Johnson R. C., Magnarelli L. A., Hyde F. W. Identification of endemic foci of Lyme disease: isolation of Borrelia burgdorferi from feral rodents and ticks (Dermacentor variabilis). J Clin Microbiol. 1985 Jul;22(1):36–38. doi: 10.1128/jcm.22.1.36-38.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Anderson J. F., Magnarelli L. A., Burgdorfer W., Barbour A. G. Spirochetes in Ixodes dammini and mammals from Connecticut. Am J Trop Med Hyg. 1983 Jul;32(4):818–824. doi: 10.4269/ajtmh.1983.32.818. [DOI] [PubMed] [Google Scholar]
  3. Barbour A. G., Hayes S. F., Heiland R. A., Schrumpf M. E., Tessier S. L. A Borrelia-specific monoclonal antibody binds to a flagellar epitope. Infect Immun. 1986 May;52(2):549–554. doi: 10.1128/iai.52.2.549-554.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Barbour A. G. Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med. 1984 Jul-Aug;57(4):521–525. [PMC free article] [PubMed] [Google Scholar]
  5. Bosler E. M., Coleman J. L., Benach J. L., Massey D. A., Hanrahan J. P., Burgdorfer W., Barbour A. G. Natural Distribution of the Ixodes dammini spirochete. Science. 1983 Apr 15;220(4594):321–322. doi: 10.1126/science.6836274. [DOI] [PubMed] [Google Scholar]
  6. Breznak J. A., Canale-Parola E. Spirochaeta aurantia, a pigmented, facultatively anaerobic spirochete. J Bacteriol. 1969 Jan;97(1):386–395. doi: 10.1128/jb.97.1.386-395.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Burgdorfer W., Barbour A. G., Hayes S. F., Benach J. L., Grunwaldt E., Davis J. P. Lyme disease-a tick-borne spirochetosis? Science. 1982 Jun 18;216(4552):1317–1319. doi: 10.1126/science.7043737. [DOI] [PubMed] [Google Scholar]
  8. Duray P. H., Johnson R. C. The histopathology of experimentally infected hamsters with the Lyme disease spirochete, Borrelia burgdorferi. Proc Soc Exp Biol Med. 1986 Feb;181(2):263–269. doi: 10.3181/00379727-181-42251. [DOI] [PubMed] [Google Scholar]
  9. Haapala D. K., Rogul M., Evans L. B., Alexander A. D. Deoxyribonucleic acid base composition and homology studies of Leptospira. J Bacteriol. 1969 May;98(2):421–428. doi: 10.1128/jb.98.2.421-428.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hyde F. W., Johnson R. C. Genetic relationship of lyme disease spirochetes to Borrelia, Treponema, and Leptospira spp. J Clin Microbiol. 1984 Aug;20(2):151–154. doi: 10.1128/jcm.20.2.151-154.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Johnson R. C., Marek N., Kodner C. Infection of Syrian hamsters with Lyme disease spirochetes. J Clin Microbiol. 1984 Dec;20(6):1099–1101. doi: 10.1128/jcm.20.6.1099-1101.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Kelly R. Cultivation of Borrelia hermsi. Science. 1971 Jul 30;173(3995):443–444. doi: 10.1126/science.173.3995.443. [DOI] [PubMed] [Google Scholar]
  13. Levine J. F., Wilson M. L., Spielman A. Mice as reservoirs of the Lyme disease spirochete. Am J Trop Med Hyg. 1985 Mar;34(2):355–360. doi: 10.4269/ajtmh.1985.34.355. [DOI] [PubMed] [Google Scholar]
  14. Loken K. I., Wu C. C., Johnson R. C., Bey R. F. Isolation of the Lyme disease spirochete from mammals in Minnesota. Proc Soc Exp Biol Med. 1985 Jul;179(3):300–302. doi: 10.3181/00379727-179-42100. [DOI] [PubMed] [Google Scholar]
  15. MARMUR J., DOTY P. Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. J Mol Biol. 1962 Jul;5:109–118. doi: 10.1016/s0022-2836(62)80066-7. [DOI] [PubMed] [Google Scholar]
  16. Magnarelli L. A., Anderson J. F., Apperson C. S., Fish D., Johnson R. C., Chappell W. A. Spirochetes in ticks and antibodies to Borrelia burgdorferi in white-tailed deer from Connecticut, New York State, and North Carolina. J Wildl Dis. 1986 Apr;22(2):178–188. doi: 10.7589/0090-3558-22.2.178. [DOI] [PubMed] [Google Scholar]
  17. Miao R. M., Fieldsteel A. H., Harris D. L. Genetics of Treponema: characterization of Treponema hyodysenteriae and its relationship to Treponema pallidum. Infect Immun. 1978 Dec;22(3):736–739. doi: 10.1128/iai.22.3.736-739.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Miao R., Fieldsteel A. H. Genetics of Treponema: relationship between Treponema pallidum and five cultivable treponemes. J Bacteriol. 1978 Jan;133(1):101–107. doi: 10.1128/jb.133.1.101-107.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Philip R. N., Casper E. A., Ormsbee R. A., Peacock M. G., Burgdorfer W. Microimmunofluorescence test for the serological study of rocky mountain spotted fever and typhus. J Clin Microbiol. 1976 Jan;3(1):51–61. doi: 10.1128/jcm.3.1.51-61.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]

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