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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Semin Nephrol. 2008 May;28(3):217–226. doi: 10.1016/j.semnephrol.2008.03.004

Figure 1. Impaired urinary concentrating ability in AQP null mice.

Figure 1

A. Sites of AQP expression in kidney. B. Twenty-four hour urine collections showing polyuria in mice lacking AQP1 and AQP3, individually and together. C. Urine osmolalities before and after 36 hour water deprivation (S.E.). D. Transepithelial osmotic water permeability (Pf) in microperfused proximal tubule, thin descending limb of Henle, and inner medullary collecting from mice of indicated genotype (S.E.). Data summarized from refs. 15–18, 20, 21.