Figure 3.
Example of fMRI responses. Top shows mean % BOLD signal change for the voxels within that cluster correlating to the mean time course for active voxels in that cluster (p<0.0005). a,b: show similar slices from two different subjects. There were 6 consecutive stimulation trains resulting in 6 peaks of activation or positive BOLD responses. These animals had 2 electrodes (stimulation and ground) approximately 2mm apart. The bottom shows the results from one cluster where the fast spin echo image is overlaid with the active voxels (orange-red) correlating to the mean time course for that cluster (p<0.0005). Arrows show the regions of the two electrodes. There was strong activation in both the ipsilateral and contralateral cortex c) Example of activation responses from an animal with a single electrode implanted near the corpus callosum. Arrow indicates the electrode site d: the same subject as in ācā showing negative activation in the cortex which extends into the striatum. There were 6 repeated trains of stimuli.
