Table 1.
All patients (n = 129) |
PAD-4– negative patients (n = 83) |
PAD-4– positive patients (n = 46) |
|
---|---|---|---|
Age, mean ± SD years | 59.4 ± 8.1 | 59.2 ± 8.0 | 59.7 ± 8.4 |
Sex, % female | 63.6 | 62.7 | 65.2 |
Ethnicity, % | |||
White | 86.0 | 84.3 | 89.1 |
African American | 8.6 | 12.0 | 2.2 |
Asian | 3.1 | 3.6 | 2.2 |
Other | 2.3 | 6.5 | |
Body mass index, mean ± SD kg/m2 | 28.5 ± 5.8 | 28.9 ± 5.7 | 27.9 ± 6.0 |
Disease duration, mean ± SD years | 12.5 ± 10.5 | 10.3 ± 9.7 | 16.3 ± 10.9† |
Shared epitope status, % | |||
None | 30.2 | 37.3 | 17.4 |
Heterozygous | 50.4 | 45.8 | 58.7 |
Homozygous | 19.4 | 16.9 | 23.9 |
CRP level, mg/liter | |||
Mean ± SD | 6.8 ± 14.2 | 5.9 ± 13.0 | 8.4 ± 16.2 |
Median | 2.7 | 2.1 | 3.9 |
ESCAPE RA = Evaluation of Subclinical Cardiovascular Disease and its Predictors of Events in Rheumatoid Arthritis; PAD-4 = peptidyl arginine deiminase type 4; CRP = C-reactive protein.
P = 0.002 versus PAD-4–negative patients.