Table 4.

Conditional and Unconditional Multivariable^* Odds Ratios and 95% Confidence Intervals for the Development of Acanthamoeba Keratitis among 30 Acanthamoeba keratitis cases and 39 clinic-matched controls wearing soft contact lenses.^*

	Conditional Multivariable Analysis*†				Unconditional Multivariable Analysis*†‡
	Conditional OR§	95% CI		Chi-square p-value	Unconditional OR**	95% CI		Chi-square p-value
Exclusive use of Complete MoisturePlus solution (compared to all other solutions)	18.51	2.11	162.63	0.008	9.36	2.42	36.21	0.001
Reuse of solution >5 times per month (compared to 0–5 times per month)	3.17	0.82	12.33	0.096	4.20	1.25	14.10	0.020
“Rub” while cleaning lenses ≤ 10 times per month (compared to >10 times per month)	9.05	0.82	100.19	0.073	3.76	0.93	15.15	0.063
Shower while wearing lenses >5 per month (compared to 0–5 times per month)	9.07	0.68	120.72	0.095	2.36	0.64	8.71	0.198
Actual contact lens replacement quarterly or more frequent (compared to less frequent than quarterly)	0.42	0.07	2.61	0.348	0.60	0.16	2.30	0.456
Age of case at replacement >3 months (compared to ≤ 3 months)	2.79	0.56	13.98	0.212	1.97	0.52	7.46	0.318

^*The same subset of complete matched case-control pairs was used in each analysis

^†Both conditional and unconditional multivariable analysis results adjusted for significant variables in univariate analysis, including exclusive use of Complete MoisturePlus solution and reuse of solution >5 times per month

^‡Unconditional analysis also adjusted for matching variables, including age (continuous) and date-of-service

^§Exact conditional logistic regression used when necessary

^**Exact unconditional logistic regression used when necessary