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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Biomaterials. 2008 Apr 29;29(21):3137–3142. doi: 10.1016/j.biomaterials.2008.04.019

Figure 1.

Figure 1

A) Dihydrazide molecules of increasing length used as spacers between peptide and surface. B) Scheme for controlled attachment of PTH(1-34) to dihydrazide-modified PLGA. Oxidation of the N-terminal serine creates an aldehyde that forms a hydrazone bond with the derivatized substrate.