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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Toxicol Appl Pharmacol. 2006 Nov 15;224(3):350–359. doi: 10.1016/j.taap.2006.11.011

Table 1.

Summary of the outcome of in vivo chemopreventive studies conducted with silymarin and silibinin against cancers of different organs/sites

Cancer site Outcome with Silymarin Outcome with Silibinin

Skin Cancer (NMSC) Positive Positive
Prostate Cancer Positive Positive
Breast Cancer Negative ND
Colon Cancer Positive ND
Lung Cancer ND Positive/No Effect
Bladder Positive ND
Ovarian Cancer ND Positive
Hepatocellular Carcinoma Positive ND
Pancreatic Cancer ND ND

ND: Not Determined.