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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Hypertension. 2008 Jun 30;52(2):359–365. doi: 10.1161/HYPERTENSIONAHA.107.104273

Figure 1.

Figure 1

Plots of P values from haplotype trend logistic regression analysis in the sample of 194 black subjects with essential hypertension, consisting of 97 good responders and 97 poor responders to hydrochlorothiazide. The -log10 P values are plotted as a function of location across the 22 autosomes (A, top), across chromosome 12 (B, middle), and across a region of chromosome 12q15 designated by reference sequence numbers of the SNPs genotyped on the Affymetrix 100K Human Mapping Array Set (C, bottom). In the bottom panel, separate horizontal lines depict the -log10 P value of each 3-SNP haplotype window above the component SNPs, and separate dots depict the -log10 P value of each SNP.