Table 2.
Estimated Frequencies of Haplotypes Constructed From Affymetrix 100K SNPs on Chromosome 12q15 Region (rs317689, rs315135, and rs7297610) Associated With Diastolic BP Response Category in Black Subjects
Observed Haplotypes |
|||||
---|---|---|---|---|---|
Response Category | ACT | ATT | ACC | GTC | ATC |
Overall | 5.6 | 23.2 | 6.0 | 12.7 | 52.5 |
Poor responders | 8.7 | 28.1 | 6.8 | 13.4 | 43.0 |
Good responders | 0.0 | 17.6 | 5.9 | 8.6 | 64.7 |
P | 0.0018 | 0.0219 | 0.421 | 0.660 | 0.00017 |
Haplotype frequencies were estimated for the good and poor responders using Haplo.Stat software, and statistical significance of differences between groups was based on a score test.19