Table 4.
Fold differences between apoptosis-related genes and housekeeping genes in normal cochleae
| Fold difference | % CV values | Fold difference | % CV values | ||
|---|---|---|---|---|---|
| Bcl-2 Family: | Traf Family: | ||||
| Bad (Bbc2) | −24.8 | 95.52 | Traf1 | −310.1 | 26.20 |
| *Bag1 | −4.4 | 48.09 | Traf2 | −22.7 | 21.47 |
| Bak1 | −45.4 | 71.98 | Traf3 | −31.2 | 49.65 |
| Bax | −9.9 | 32.12 | Traf4 | −62.4 | 43.53 |
| Bcl2 | −14.7 | 26.06 | Card Family | ||
| Bcl2a1 | −647.3 | 47.39 | Apaf1 | −198.1 | 78.72 |
| *Bcl2l1 | −2.3 | 35.79 | Bcl10 | −26.9 | 36.69 |
| Bcl2l2 | −19.4 | 71.70 | Card6 | −11.7 | 20.65 |
| Bcl2l11 | −2421.5 | 92.41 | Card10 | −35.3 | 42.48 |
| Bclaf1 | −7.3 | 26.89 | Cradd | −66.5 | 27.21 |
| Bld | −31 | 48.97 | Nol3 | −73.3 | 59.14 |
| Bid3 (Hrk) | −89.7 | 75.42 | Pycard (Asc) | −26.9 | 34.32 |
| Blk | −30.8 | 47.35 | Ripk2 | −13.9 | 38.52 |
| Bnip1 | −23.1 | 25.52 | Death Domain Family: | ||
| Bnlp2 | −18.3 | 25.01 | Dapk1 | −35.2 | 39.08 |
| *Bnlp3 | −3 | 22.05 | Fadd | −20.3 | 16.76 |
| Bok | −19.6 | 51.55 | Tradd | −30.4 | 33.62 |
| *Mcl1 | −4.6 | 34.10 | CIDE Domain Family: | ||
| TNF Ligand and Receptor Family: | Cidea | −41.5 | 46.15 | ||
| Lta | −4973.3 | 136.81 | Cideb | −353.8 | 95.87 |
| Tnf | −495.7 | 59.90 | Dffa | −58.6 | 30.70 |
| Tnfsf10 | −67.5 | 29.48 | Dffb | −2288.2 | 55.08 |
| Tnfs12 | −26.3 | 50.94 | p53 and DNA Damage-Induced Apeptosis: | ||
| Cd40lg (Tnfsf5) | −8974.8 | 125.23 | Gadd45a | −.30.3 | 82.30 |
| Faslg (Tnfsf6) | −855.1 | 54.81 | Tp53 (p53) | −29 | 43.75 |
| Ltbr | −13.4 | 45.01 | Trp53bp2 | −35.4 | 58.62 |
| Tnfrsf10b | −564.2 | 57.95 | Trp63 | −2906.4 | 76.92 |
| Tnfrsf11b | 1.6 | 17.92 | TAP Family: | ||
| Tnfrsf1a | −19.1 | 33.24 | Birc1b | −1093.7 | 50.56 |
| Tnfrsf1b | −354.2 | 28.20 | Birc3 | −502 | 74.13 |
| Tnfrsf5 | −489.4 | 27.17 | *Birc4 | −5.9 | 45.48 |
| Tnfrsf6 | −826 | 35.40 | Birc5 | −248.7 | 26.45 |
| Caspase Family: | Others with anti-apoptotic function: | ||||
| Casp1 | −197.9 | 68.78 | Trp73 | −12245.8 | 68.13 |
| Casp2 | −34.6 | 32.67 | *Apl5 | −4.2 | 21.55 |
| Casp3 | −14 | 27.27 | Aven | −29.3 | 42.03 |
| Casp6 | −16.1 | 13.36 | *Dad1 | −4.2 | 32.11 |
| Casp7 | −238.3 | 50.61 | Falm | −45.8 | 33.88 |
| Casp8 | −129.6 | 39.86 | ll10 | −1619.9 | 79.89 |
| Casp8ap2 | −296.1 | 102.86 | Lhx4 | −1335.7 | 100.69 |
| Casp9 | −24.4 | 17.93 | *Mapk8lp | −1.9 | 38.97 |
| Casp4 (Casp11) | −8.5 | 39.47 | Nfkb1 | −10.5 | 38.41 |
| Casp12 | −10.5 | 38.26 | Polb | −74.5 | 50.60 |
| Casp14 | −12245.8 | 43.65 | *Prdx2 | 1 | 30.36 |
| Death Effecter Domain Family: | Prlr | −2804.1 | 50.63 | ||
| *Cflar | −5 | 16.80 | Prok2 | −2873 | 60.98 |
| Sphk2 | −10.5 | 33.71 | |||
Note: Asterisks point to 1he 10 antl-apoptolic genes