Figure 2.
NMDAR- and AMPAR-mediated EPSCs peak amplitude in CA1 pyramidal neurons of mutant and control mice. The ratio of NMDAR- to AMPAR-mediated EPSCs (A), AMPAR- (B) and NMDAR-mediated (C) currents did not differ between the two genotypes, indicating that the mutation did not affect the efficacy of AMPAR and NMDAR mediated neurotransmission in CA1 pyramidal neurons. All values refer to mean ± standard error of the mean (SEM).