Table 4.

IC₅₀ −log M values and response to 10⁻⁴ M ACh of soleus muscle feed arteries from young and old rats used in the exercise training study

Parameter	Con	l-NNA	Indo	l-NNA + Indo
IC50, −log M ACh
Young Sed	−7.75±0.27	−6.97±0.26	−7.37±0.26	−7.06±0.38
Young Ex	−7.53±0.30	−6.91±0.18	−7.25±0.29	−6.47±0.45
Old Sed	−7.52±0.35	−7.13±0.16	−6.55±0.24	−6.5±0.73
Old Ex	−7.83±0.55	−7.15±0.26	−7.20±0.60	−6.55±0.60
Response to 10−4 M ACh, % possible dilation
Young Sed	87.0±6.2	52.4±8.2a	64.6±9.3	60.6±8.8a
Young Ex	76.9±10.7	49.1±12.6a	73.6±9.4d	28.1±8.6a,c
Old Sed	54.2±8.7f	37.9±6.0	67.4±9.0b,d	28.5±11.1c
Old Ex	80.9±6.8b,e	41.8±9.5a	61.8±11.3	39.1±8.3a

Values are means ± SE; n = 8–10 rats/group. Significantly different from

^aCon,

^bL-NNA,

^cIndo,

^dl-NNA+ Indo,

^eSed,

^fYoung, P ≤ 0.05.