Table 5.

IC₅₀ −log M values and response to 10⁻⁴ M ACh of soleus muscle feed arteries from young and old rats used in the antioxidant studies

Parameter	Con	SOD	SOD + CAT	SOD + l-NNA
IC50, −log M ACh
Young	−6.61±0.20	−7.28±0.26	−6.72±0.20	−8.18±0.62a,c
Old	−7.01±0.18	−7.39±0.14	−7.44±0.35	−7.33±0.46
Response to 10−4 M ACh, % possible dilation
Young	72.5±4.7	78.7±5.4d	64.9±9.3	52.7±13.2b
Old	44.1±5.3b,c,e	72.9±6.6a,d	72.8±7.1a,d	27.2±4.5b,c

Values are means ± SE; n = 6–21 rats/group. Significantly different from

^aCon,

^bSOD,

^cSOD + CAT,

^dSOD + l-NNA,

^eYoung, P ≤ 0.05.