Table 1.
Length, μm | SS fraction, % | k1, s−1 | k2, mM−1 ·s−1 | Avg Nondimensional O2 Concn | Avg Nondimensional ATP Concn | η | ATP Turnover Rate, mM/min | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Light fiber | ||||||||||||||
40 | 48 | 0.0009 | 0.86 | 0.94 | 0.86 | 0.99 | 0.47 | |||||||
40 | 0 | 0.0009 | 0.86 | 0.90 | 0.86 | 0.99 | 0.46 | |||||||
300 | 88 | 0.005 | 0.186 | 0.55 | 0.16 | 0.77 | 0.47 | |||||||
300 | 0 | 0.005 | 0.186 | 0.20 | 0.05 | 0.26 | 0.16 | |||||||
Dark fiber | ||||||||||||||
17.5 | 75 | 0.005 | 1.10 | 0.96 | 0.61 | 0.99 | 1.84 | |||||||
17.5 | 0 | 0.005 | 1.10 | 0.92 | 0.59 | 0.98 | 1.80 | |||||||
300 | 75 | 0.012 | 14.9 | 0.065 | 0.25 | 0.32 | 1.84 | |||||||
300 | 0 | 0.012 | 14.9 | 0.027 | 0.13 | 0.17 | 0.98 |
SS, subsarcolemma; k1, ATPase rate constant; k2, oxidative phosphorylation rate constant. Data are based on experimentally determined diffusion path lengths and phosphagen recovery rates (6, 24, 30, 38). Output was obtained at the lowest values of k1 that would satisfy the observed rate, which maximized η. ATP turnover rate is fixed in the observed case (SS mitochondrial fraction =48, 88, or 75%), and k1 and k2 values from these observed cases are used in the hypothetical cases with only intermyofibrillar mitochondria (SS mitochondrial fraction = 0).