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Isolated tracheal epithelial cell PKC activity in saline and DE (12.5%)-treated mice. PKCα (A) and PKCɛ (B) activity demonstrated 5 h after single inhalation of DE (12.5%) and saline in mice. PKCα (C) and PKCɛ (D) activity after 2 wk of once-daily DE exposure, 5 h after last dose. Error bars are SE (n = 6 mice minimum/group). *P < 0.05 is statistically significant of DE vs. saline-treated mice.
