TABLE 2.

Plasma biomarkers of oxidative stress and inflammation

	Control subjects	T1DM patients	T1DM-MV patients
n	54	54	48
hsCRP (mg/l)	0.95	1.7*	2.6*†
sVCAM (ng/ml)	106.6 ± 16.8	122 ± 24.7	128 ± 34.6*†
sICAM (ng/ml)	25 ± 10.1	25.3 ± 7.3	29.3 ± 9.6*
sCD40L (ng/ml)	0.46 (0.13–0.63)	0.51 (0.31–0.78)	0.57 (0.26–0.54)
E-selectin (ng/ml)	10.2 ± 3.8	13.5 ± 5.1*	14.5 ± 3.5*
Nitrotyrosine (ng/ml)	119 ± 78	291.8 ± 125.8*	505.1 ± 232.6*†

Data are means ± SD or median (interquartile range) unless otherwise indicated.

^*P < 0.05 compared with control subjects, and

^†P < 0.05 compared with T1DM patients by one-way ANOVA followed by Bonferroni’s post-test.