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Affinity of Cu(II)-CB-TE2A-c(RGDyK) [30] and Cu(II)-DiamSar-c(RGDfD) for integrin αvβ3 as determined in heterologous competitive binding assay using biotinylated vitronectin (c(RGDyK) [30] was used as a control).
| Compound | IC50 (nM) | 95% Confidence Intervals (nM) |
|---|---|---|
| Cu(II)-CBTE2A-c(RGDyK) | 6.0 | 3.7-9.6 |
| Cu(II)-DiamSar-c(RGDfD) | 4.8 | 3.9-5.8 |
| c(RGDyK) | 3.7 | 2.7-5.0 |
