Table 2.
Immunoglobulin gene usage for variable heavy chain of anti-V3 mAbs
| mAb | Cells | IGHV | IGHD | D-RF | IGHJ | Reference |
|---|---|---|---|---|---|---|
| 419-D | Hybridoma | 5-51*01 | 6-19 | 3 | 4 | (Gorny et al., 1993) |
| 782-D | “ | 5-51*01 | 5-24 | 1 | 4 | (Gorny et al., 1997) |
| 838-D | “ | 5-51*01 | 2-2 | 2 | 4 | (Gorny et al., 1997) |
| 908-D | “ | 5-51*01 | 1-14 | 2 | 4 | (Gorny et al., 1997) |
| 2456c | “ | 5-51*01 | 3-22 | 2 | 3 | (Gorny et al., 2002) |
| 2557a | “ | 5-51*01 | 3-22 | 2 | 3 | (Gorny et al., 2004) |
| 3906a | “ | 5-51*01 | 3-22 | 3 | 3 | This study |
| 4022a | “ | 5-51*01 | 2-8 | 2 | 5 | This study |
| 4025a | “ | 5-51*01 | 3-3 | 1 | 6 | This study |
| 257-2D | EBV | 5-51*03 | 3-22 | 2 | 4 | (Andris et al., 1991) |
| 1006-15D | Hybridoma | 5-51*03 | 3-22 | 2 | 3 | (Gorny et al., 1997) |
| 2219b | “ | 5-51*03 | 4-17 | 2 | 3 | (Gorny et al., 2002) |
| 2483b | “ | 5-51*03 | 3-10 | 2 | 3 | (Gorny et al., 2004) |
| 2558a | “ | 5-51*03 | 1-26 | 3 | 4 | (Gorny et al., 2004) |
| 3019a | “ | 5-51*03 | 2-21 | 2 | 3 | (Gorny et al., 2006) |
| 3694a | “ | 5-51*03 | 3-9 | 2 | 1 | This study |
| 4085a | “ | 5-51*03 | 2-21 | 2 | 4 | This study |
| 3792a | “ | 5-51*03 | 3-22 | 2 | 4 | This study |
| 447-52D | “ | 3-15*07 | 3-10 | 3 | 6 | (Lewis et al., 1995) |
| MN215 | EBV | 3-21*01 | 2-21 | 3 | 4 | (van der Donk et al., 1994) |
| 2601a | Hybridoma | 3-30*02 | 2-2 | 2 | 4 | (Gorny et al., 2006) |
| 504-D | “ | 3-30*03 | 3-16 | 2 | 3 | (Gorny et al., 1993) |
| 1324Ea | “ | 3-30*03 | 2-15 | 3 | 5 | (Gorny et al., 1998) |
| 3904a | “ | 3-30*03 | 3-16 | 3 | 4 | This study |
| 412-D | “ | 3-33*01 | 3-10 | 1 | 6 | (Gorny et al., 1993) |
| 2424 | “ | 3-53*01 | 5-12 | 3 | 6 | (Gorny et al., 2004) |
| 418-D | “ | 3-53*03 | 3-22 | 2 | 6 | (Gorny et al., 1993) |
| F425 | “ | 3-64*01 | 3-22 | 2 | 3 | (Liu et al., 2003) |
| 537-D | “ | 3-7*01 | 2-2 | 2 | 6 | (Gorny et al., 1993) |
| 3402 | “ | 3-7*02 | 3-22 | 2 | 6 | This study |
| 3791a | “ | 1-18*01 | 4-17 | 2 | 4 | This study |
| 4121a | “ | 1-18*01 | 1-1 | 2 | 4 | This study |
| 391/95-D | “ | 1-24*01 | 3-3 | 1 | 4 | (Gorny et al., 1993) |
| 311-11D | “ | 1-3*01 | 3-10 | 2 | 4 | (Gorny et al., 1993) |
| 1334 | “ | 1-3*01 | 3-9 | 2 | 4 | (Gorny et al., 2000) |
| 1027-15D | “ | 1-f*01 | 3-3 | 2 | 5 | (Gorny et al., 1997) |
| 2191 | “ | 1-f*01 | 3-3 | 2 | 5 | (Gorny et al., 2002) |
| 3224a | “ | 1-f*01 | 6-19 | 2 | 6 | (Gorny et al., 2006) |
| 3697a | “ | 1-f*01 | 5-24 | 3 | 4 | This study |
| 3869a | “ | 1-f*01 | 2-15 | 2 | 4 | This study |
| DO142 | Phage | 1-f*01 | 2-15 | 2 | 4 | (Ditzel et al., 1997) |
| 268-11D | EBV | 4-59*01 | 5-12 | 3 | 3 | (Andris et al., 1991) |
| 386-D | Hybridoma | 4-59*01 | 2-8 | 3 | 4 | (Gorny et al., 1993) |
| 453-D | “ | 4-59*01 | 2-15 | 3 | 3 | (Gorny et al., 1993) |
| 1108 | “ | 4-59*01 | 2-15 | 3 | 3 | (Zolla-Pazner et al., 1999) |
| 2442 | “ | 4-59*01 | 6-13 | 1 | 4 | (Gorny et al., 2002) |
| 3074a | “ | 4-59*01 | 3-22 | 2 | 3 | (Gorny et al., 2006) |
| 3881a | “ | 4-59*01 | 2-2 | 3 | 3 | This study |
| 2182a | “ | 4-59*04 | 2-15 | 3 | 3 | (Gorny et al., 2002) |
| 2412c | “ | 2-5*04 | 3-22 | 2 | 4 | (Gorny et al., 2002) |
| 694/98-D | “ | 2-5*04 | 5-12 | 3 | 4 | (Gorny et al., 1992) |
a
mAbs derived from non-clade B HIV-1 infected individuals living or being infected abroad.
b,c
These mAbs were generated from blood samples derived from one patient at different time. D-RF, D gene reading frame.