Table 1.
The combination indexes (CI) for each cytotoxic agent combined with sHA14-1 in Jurkat cell line.
| Treatment | CI | |
|---|---|---|
| Fas | IC50 |
0.05 ± 0.02 |
| 0.75 × IC50 |
0.24 ± 0.10 | |
| 0.5 × IC50 | 0.44 ± 0.13 | |
|
| ||
| Dex | IC50 | 0.78 ± 0.03 |
| 0.75 × IC50 | 0.71 ± 0.02 | |
| 0.5 × IC50 | 0.89 ± 0.04 | |
Dexamethasone (Dex) and Fas ligand (Fas) were combined with sHA 14-1 (sHA) at a fixed dose ratio (molar ratio of sHA 14-1: Dex = 1:10,000 and ratio of sHA 14-1: Fas = 20,000 M:1 g/ml respectively) to treat the cells and cell viability was assessed by Cell-Titer Blue Viability Assay or long-term survival colony assay. Data were analyzed as described. Data shown are means ± S.D. of the CI values obtained at the IC50, 0.75 × IC50, and 0.5 × IC50.