| Inhibition of protein C activity (acquired protein C resistance) |
| Inhibition of protein S cofactor activity |
| Inhibition of antithrombin activity |
| Induction of tissue factor in endothelial cells and monocytes |
| Inhibition of tissue factor pathway inhibitor |
| Inhibition of endothelial cell prostacyclin synthesis |
| Increased deposition of prothrombin leading to increased thrombin formation |
| Deposition of immune complexes |
| Inhibition of tPA activity |
| Inhibition of fibrinolysis via interaction with antiplasmin |
| Activation of factor XI |
| Induction of platelet aggregation |
| Disturbance of a protecting annexin A5 shield |
| Induction of microparticle formation |
| Induction of endothelial cell adhesion receptors |
| Complement activation |
