Table 2. Average physiological parameters of the rats tested in various treatment groups. The values are given as mean±SD.
| Sham operated groups1 | OBX groups2 | |||||
|---|---|---|---|---|---|---|
| SVV (n=9) |
SCV (n=10) |
SCP (n=9) |
XVV (n=10) |
XCV (n=7) |
XCP (n=8) |
|
| Weight gain (g) | 81 ±13§ | 82 ±14§ | 81 ±11§ | 62.2 ±5.4 | 62 ±17 | 66 ±22 |
| PaO2 | 88.1 ±5.4 | 92.3 ±2.8 | 91.1 ±4.6 | 91 ±10 | 88.6 ±8.3 | 88 ±11 |
| PaCO2 | 36.8 ±1.8 | 37.1 ±5.1 | 41.0 ±3.3 | 37.3 ±1.9 | 41.5 ±2.9 | 39.8 ±3.1 |
| pH | 7.45 ±0.02¶ | 7.43 ±0.02† | 7.40 ±0.03 | 7.43 ±0.03‡ | 7.40 ±0.02 | 7.38 ±0.02 |
| Hematocrit (%) | 44 ±3 | 46 ±5 | 47 ±2 | 45 ±5 | 48 ±6 | 47 ±3 |
| Total Trp (nmol/mL) | 43 ±11.0¶¶ | 66.4 ±5.2 | 67.9 ±8.5 | 45.0 ±7.2 | 73 ±11# | 67 ±12 |
| Free Trp (nmol/mL) | 7.4 ±2.12 | 9.2 ±2.4 | 8.9 ±2.5 | 7.9 ±2.8 | 8.9 ±2.3 | 10.3 ±0.9 |
The sham groups are: SVV, sham rats treated with vehicle for both citalopram and pindolol; SCV, sham rats treated with citalopram and vehicle for pindolol; SCP, sham rats treated with both citalopram and pindolol. n=number of rats per group.
The OBX groups are: XVV, OBX rats treated with vehicle for both citalopram and pindolol; XCV, OBX rats treated with citalopram and vehicle for pindolol; XCP, OBX rats treated with both citalopram and pindolol. n = number of rats per group.
Significantly different from respective OBX group.
Significantly different from the value in the SCP group.
Significantly different from both SCV and SCP groups
Significantly different from the value in the SCP group.
Significantly different from the value in the XCP group.
Significantly different from both XVV and XCP groups.