Skip to main content
. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: ChemMedChem. 2008 Aug;3(8):1250–1268. doi: 10.1002/cmdc.200800047

Scheme 4.

Scheme 4

Synthesis of compounds 26–31: a) Phenylboronic acid, Cu(OAc)2, Et3N, CH2Cl2, air, rt, 16 h; b) OsO4, NMO, THF, rt, overnight; c) BBr3, CH2Cl2, −78 °C, 2h; d) H2, Pd/C, EtOAc, rt, 2h; e) NaBH4, MeOH, 0 °C, 1h; f) amine, NaBH(OAc)3, AcOH, CH2Cl2, rt, overnight.