Skip to main content
. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Biomaterials. 2007 Nov 26;29(8):1054–1064. doi: 10.1016/j.biomaterials.2007.11.003

Table 1.

Comparative mechanical properties among gel systems from degradable polymers used for cell encapsulation.

Material Traditional Modulus (KPa) Literature
Silk hydrogels 369–1712 This study
Fibrinogen - PEG copolymer1 0.02–4 27
Poly(1,8-octanediol citrate) (POC)2 10.4 40
PEG dimethacrylate-PLA copolymer, (photocrosslinked) 3 60–500 39
Gelatin4 0.18 42
Gelatin, glutaraldehyde cross-linked4 8.13 42
Dex-AI/PNIPAAm5 5.4–27.7 43
Alginate6 ~25–125 28
Material Equilibrium Modulus (KPa) Literature
Silk hydrogels 63–441 This study
Agarose (2% final concentration)7 ~ 15 26
1

5mm dia × 5 mm height. Deformation rate of 1.5 mm/min, modulus based on average slope of the lower portion of stress-strain curve (<15%).

2

6mm dia × 2.4 mm height. Deformation rate of 2mm/min, modulus based on average slope of the initial portion of stress-strain curve.

3

5mm dia × 1mm height. Load-controlled deformation rate of 40 to 100 mN/min.

4

12.5mm dia × 1.5 mm height. Load-controlled deformation rate of 25 mN/min, Young’s modulus equivalent to the absolute value of the slope obtained between initial preload force (.01N) to .25N.

5

6mm dia. Deformation rate of .5 mm/min, modulus based on average slope of the lower portion of stress-strain curve.

6

Deformation rate of 1mm/min. Elastic moduli were obtained from the slope of the stress vs. strain curves, limited to the first 10% of strain.

7

Equilibrium modulus calculated from the equilibrium stress and initial cross-sectional area at 10% strain.