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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Nat Neurosci. 2004 Jul 11;7(8):812–818. doi: 10.1038/nn1283

Figure 4.

Figure 4

Increased innervation of proprioceptive target tissues in TrkATrkC/TrkC mice. (a,b) Parvalbumin antibody staining marks the central projections of DRG neurons in wild-type and TrkATrkC/TrkC mice. The axonal projections converging toward the intermediate and ventral spinal cord (arrows) are denser in the L5 region of TrkATrkC/TrkC mice. (c-f) Hematoxylin- and eosin- stained paraffin sections through the soleus muscle show an increased number of spindles (arrows) in the TrkATrkC/TrkC (d) and TrkATrkC/TrkC;Myo/NT3 (f) mice at P5 (c,d) and P0 (e,f). (g,h) Parvalbumin-positive muscle spindles within the back muscles at the L5 level of newborn Myo/NT3 (g) and TrkATrkC/TrkC;Myo/NT3 (h) mice. Scale bars are 50 μM.