Table 2.
Effects of fluvoxamine (FLU) alone and ranitidine (RAN) alone on tGSH, NO, MPO, and MDA levels in the stomach tissues of rats.
| Drugs | Dose (mg/kg) |
tGSH | MDA | NO | MPO |
|---|---|---|---|---|---|
| FLU | 25 | 14.9 ± 0.6 | 2.1 ± 0.3 | 80.4 ± 6.3 | 1.0 ± 0.02 |
| FLU | 50 | 15.1 ± 0.3* | 1.8 ± 0.2* | 95.2 ± 4.5* | 0.8 ± 0.04* |
| FLU | 100 | 17.1 ± 0.8* | 1.7 ± 0.3* | 99.7 ± 5.7* | 0.5 ± 0.03* |
| FLU | 200 | 18.3 ± 0.6* | 1.6 ± 0.2* | 105.1 ± 5.2* | 0.4 ± 0.01* |
| RAN | 50 | 15.8 ± 0.4* | 2.1 ± 0.5* | 96.8 ± 4.7* | 0.6 ± 0.03* |
| Intact (Control) | - | 12.7 ± 0.2 | 2.3 ± 0.4 | 83.4 ± 3.6 | 1.1 ± 0.05 |
*Significant at p < 0.05 when compared to intact control.