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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: J Neurosurg. 2008 Nov;109(5):849–855. doi: 10.3171/JNS/2008/109/11/0849

Figure 4. Representative photographs and microscopies of brainstem gliomas in adult (A, B, and C) and young (D, E, and F) rats.

Figure 4

A. Depicted is the relatively focal lesion with a displacement of long tract in an adult rat harboring brainstem tumor. B and C: Hematoxylin and eosin stain of brainstem cross section of an adult rat revealed highly cellular lesions invading the white matter with a relatively clear boundary. Abundant necrosis was consistently observed (B, magnification ×1; C, magnification ×10). D. Depicted is the enlargement of the entire brainstem without focal lesion in a young rat harboring brainstem tumor. E and F: Hematoxylin and eosin stain of brainstem cross section of a young rat revealed more infiltrative and diffuse lesion, with a high degree of brainstem parenchyma invasion. Endothelial proliferation was evident and angiogenesis were frequently observed (E, magnification ×1; F, magnification, ×10).