. Author manuscript; available in PMC: 2010 May 19.

Published in final edited form as: Biochemistry. 2009 May 19;48(19):4150–4158. doi: 10.1021/bi900168m

Table 1.

A summary of peptides showing significant change in deuterium uptake upon ligand binding. X indicates significance.

Ligand	Cholesterol sulfate	Cholesterol	24S- hydroxy- cholesterol	Adx with substrate-free CYP46A1	Adx with cholesterol sulfate-bound CYP46A1
Peptide	Cholesterol sulfate	Cholesterol	24S- hydroxy- cholesterol	Adx with substrate-free CYP46A1	Adx with cholesterol sulfate-bound CYP46A1
50–64	X		X
65–80	X	X	X
109–116	X	X	X
117–125	X		X
129–143	X		X
144–150				X	X
151–164	X	X	X
225–239	X			X
260–270			X
265–276				X	X
301–313				X	X
351–361	X	X		X
362–373	X
364–373	X		X
445–455	X