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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Biochemistry. 2009 Mar 10;48(9):1975–1983. doi: 10.1021/bi802068s

Figure 5.

Figure 5

3D structural models of bZIP domains of Jun-Fos heterodimer in complex with dsDNA oligos containing the TGACGCA motif in two possible orientations I (a) and II (b). The two orientations are related by a 180°-rotation of the Jun-Fos heterodimer about the dyad axis of symmetry. The backbones of LZ and BR subdomains of the bZIP heterodimer are colored brown and blue, respectively. The backbone of dsDNA is shown in yellow. The sidechains of R263 in Jun and K148 in Fos are colored green. The guanine at position +1 (G+1) in the sense strand TGACGCA and thymine at position +1 (T+1) in the antisense strand TGCGTCA are colored red. Insets show close-up views of contacts between specific bZIP residues with DNA bases.