Table 1.

Baseline characteristics of the patients in the present substudy (n=184) and of the remaining patients enrolled in RESOLVD (n=584)

	n=184 (present substudy)	n=584 (remaining patients in RESOLVD)	p value
Age, years	66±10	62±11	<0.01
Male, %	85	83	0.82
Etiology of heart failure, %			<0.01
Ischemic heart disease	82	69
Idiopathic dilated cardiomyopathy	12	19
Other	6	12
New York Heart Association functional			0.40
class, %
II	61	64
III or IV	39	36
Heart rate, bpm	76±12	76±13	0.69
Systolic blood pressure, mm Hg	124±18	120±17	<0.01
Diastolic blood pressure, mm Hg	74±9	73±10	0.29
6-minute walk distance, m	370±86	385±83	0.06
Creatinine, μmol/l	107±24	111±40	0.29
Left ventricular end-diastolic volume, ml	234±91	263±116	<0.01
Left ventricular end-systolic volume, ml	171±83	199±107	<0.01
Left ventricular ejection fraction, %	29±10	27±11	<0.01

Data presented as percentages or mean±standard deviation.