. Author manuscript; available in PMC: 2009 Jun 8.

Published in final edited form as: Eur J Heart Fail. 2008 Jan 29;10(2):125–128. doi: 10.1016/j.ejheart.2007.12.002

Table 3.

Relationship between plasma levels of MMP, TIMP, and neurohormones

Spearman's rank correlation coefficient (ρ)	ANP	BNP	Angiotensin II	Aldosterone	Epinephrine	Norepinephrine	Endothelin-1
MMP-2	0.39 ^*	0.31^*	−0.13	0.01	0.09	0.07	0.16^¶
MMP-9	0.09	0.04	0.11	0.15^¶	0.02	−0.03	0.03
TIMP-1	0.31^*	0.22 ^†	−0.12	−0.09	0.02	0.09	0.23 ^†
MMP-2: TIMP-1	0.19 ^†	0.18 ^†	−0.03	0.03	0.09	−0.01	−0.03
MMP-9: TIMP-1	0.00	−0.03	0.15^¶	0.17^¶	0.01	−0.05	−0.05

Statistically significant correlations are marked:p<0.001,

^†

Statistically significant correlations are marked:p<0.01,

^¶

Statistically significant correlations are marked:p<0.05.

ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinase.