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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: J Comb Chem. 2009;11(1):91–102. doi: 10.1021/cc800092y

Scheme 2.

Scheme 2

Synthetic scheme of the new Fmoc-cross-linker. Reagents and reaction conditions: (i) (Boc)2O, dioxane; (ii) Fmoc-Lys (Boc)-OH, DCC, HOBt, THF; (iii) TFA / DCM; (iv) acryloxy chloride, DCM, TEA, 0°C.