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(A) Structures of the antagonists used in the binding study. (B) Inhibition of the binding of [3H]AMPA to GluR2 S1S2 by DNQX, CNQX, UBP277, and UBP282. The IC50 values were: 0.38 ± 0.04 μM, 0.68 ± 0.06 μM, 135 ± 12 μM, 292 ± 26 μM, respectively.
