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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Biologicals. 2009 Mar 12;37(3):141–147. doi: 10.1016/j.biologicals.2009.02.019

Figure 5.

Figure 5

Protection following prime/boost vaccination. A prime and boost vaccination with H1/JVRS-100 shows protection following a 6xLD50 lethal viral challenge. Balb/c mice (n=5) were vaccinated IM on day 0 and 14 with 5μg H1 or 5μg H1 combined 20μg JVRS-100. Fourteen days following the last vaccination, mice were challenged intranasally with 6xLD50 of PR/8/34 (H1N1) virus and monitored over 20 days for body weight (A) and survival (B).